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Senior/Scientist, Antibody Engineering

We are seeking an experienced and highly motivated Scientist with strong hands-on experience in antibody discovery and antibody engineering to join us.

Responsibilities:

  • Drive efforts to isolate, clone, and build new molecules to support biological therapeutics programs and early target discovery efforts across multiple disease areas. 
  • Lead engineering and humanization of novel antibody therapeutics, design of new assays to support the development, testing and functional analysis of lead candidates, use of techniques employing molecular biology, biochemistry, structural modeling for antibody affinity maturation and antibody stabilization.

Requirements:

  • PhD with 5-7 years, or MS with 7-10 years of experience in Molecular Biology, Biochemistry, Structural Biology, Immunology or related discipline.
  • Industry experience strongly preferred.
  • Prior experience leading therapeutic antibody discovery projects
  • Experience in structure modeling of antibodies
  • Experience in the design, execution, and analysis of immunological, biochemical, molecular, and/or cellular assays, such as ELISA, FACS and Western Blot.
  • Expertise utilizing techniques for antibody engineering, antibody humanization, affinity maturation and antibody stabilization.
  • Familiarity with antibody properties and sequences.
  • Experience in cell biology, including mammalian cell culture, cell transfection, and protein expression.
  • Experience in molecular biology techniques such as cloning, RT-PCR, vector construction, NGS and sequence analysis.
  • Familiar with computational tools for molecular biology and database management.
  • Strong written and verbal communication skills.
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