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Scientist, Research Antibody Division

We are seeking an experienced and highly motivated scientist to drive antibody discovery in a stand-alone subsidiary of Abpro focused on reagent generation. The successful candidate will have hands-on experience with mouse-based antibody discovery (hybridoma technology), as well as protein analytics and antibody purification. Candidates with additional experience in humanization and antibody engineering are preferred.

Responsibilities:

Responsibilities will include generating antibodies against customer-provided antigens, assaying antibodies for binding/activity, and purifying antibodies (small scale). The ideal candidate must have experience immunizing mice and generating antibodies using traditional hybridoma technology. They must be self-motivated, well organized, have an ability to work on multiple projects in parallel, and have strong communication skills.

Requirements:

  • PhD with 3-5 years, or MS with 5-7 years of related experience in immunology, cell biology, or biochemistry
  • Extensive hands-on experience and knowledge in all phases of mouse-based antibody discovery (hybridoma technology)
  • Competency in mouse handling and tissue extraction
  • Proficiency in mammalian cell tissue culture
  • Hands-on experience with binding assays (e.g., ForteBio Octet, Biacore, ELISA, flow cytometry, Luminex) and cell-based functional assays
  • Use of scientific databases and applications for data management and data analysis
  • Proficiency with protein purification methods preferred (Protein A, ion-exchange, size exclusion)
  • Experience with B-cell cloning, next-generation sequencing, humanization, or antibody engineering a plus
  • Self-motivated and collaborative, with excellent time and project management skills
  • Excellent written and verbal communication skills, along with the ability to effectively work with internal and external customer
  • Ability to advance multiple projects in a fast-paced excellence-driven environment

 

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